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In this webinar, we will discuss how to use genetically engineered mouse models (GEMMs) to move your development program from discovery stage to the clinic, including how to use:
- Conditional knockout mice to screen candidates in discovery
- Humanized immune checkpoint models for proof of concept and initial in vivo screening
- CDX and PDX engraftment in immunocompromised mice to generate efficacy and safety data
- Dr. Moore and Dr. Suryani Chen will also share data from recent studies validating the use of various models.
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